The hormone progesterone in vitro fertilization (IVF) (English in vitro fertilization) patients to help create a favorable uterine environment for embryo implantation and pregnancy in ongoing. Progesterone may be administered in several different ways, including as a tablet, a vaginal suppository or intramuscular injection into the hip or buttocks. Side effects vary depending on the route of administration.
PMS symptoms similar to
Most women experience only minor taking progesterone as part of IVF treatment, since it is used for a relatively short time side effects. On the other hand, patients who take it for the relief of symptoms of bleeding of endometriosis or to treat menstrual irregularities take the medication longer. The use of progesterone with IVF stops immediately if the pregnancy test is negative. If the pregnancy test is positive, progesterone continues to be used during the first nine to twelve weeks of pregnancy until the placenta produces enough progesterone itself to maintain pregnancy.
The most common side effects of progesterone are those that can mimic PMS (premenstrual syndrome or PMS). Patients may experience headaches, bloating, irritability, breast tenderness, drowsiness, depression and mood swings. Because these symptoms can be caused by a period approaching or pregnancy, patients are advised to remain on their post-IVF drugs until after the pregnancy test.
Side effects of muscle injectionSave Medioimages / Photodisc / Photodisc / Getty Images
When progesterone is prepared in liquid form for injection into the muscle, the liquid used is an oil to accompany. While progesterone in oil has not been approved for use in in vitro fertilization by the Food and Drug Administration (FDA), some doctors still prefer to progesterone in the traditional way, as it makes progesterone levels in the blood are higher than with other methods.
Intramuscular injections produce reliable serum progesterone, which is reassuring for the physician and patient. However, many patients find these painful intramuscular injections. Some patients have an allergic reaction to oil, develop hives, rashes or painful lumps at the injection site. Patients who experience these symptoms should inform the doctor so they can switch to alternative progesterone treatment.
vaginal side effects
Administration of vaginal progesterone has fewer side effects than intramuscular administration effects, but also produces lower levels of progesterone in the blood, providing less calm for the patient and physician as levels of local uterine progesterone are not sufficiently high to maintain pregnancy.
If progesterone is administered as a suppository or vaginal cream, vaginal irritation is a possible side effect. Some women find that creams are messy and unpleasant to use. Some women experience yeast infections when using progesterone. Vaginal dryness is another possible side effect of taking progesterone.
cardiovascular side effectsSave Dynamic Graphics / Creatas / Getty Images
Rarely, patients may experience side effects that threaten the life of use of progesterone related to the formation of blood clots. Serious side effects include persistent pain in the calf, shortness of breath, sharp chest pain and coughing up blood. Symptoms of stroke, such as sudden blindness, sudden headache, vomiting, dizziness with or without fainting, sudden weakness in the limbs or speech problems require immediate medical attention.